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ISET FOR EARLY DIAGNOSIS OF SOLID CANCERS BEFORE IMAGING

ISET FOR PREDICTIVE ONCOLOGY

Messaritakis I. et al.
Cancer Chemother Pharmacol 2018
Prognostic significance of CEACAM5mRNA-positive circulating tumor cells in patients with metastatic colorectal cancer.

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Kallergi G. et al.
Breast Cancer Research (2018) 20:67
Evaluation of α-tubulin, detyrosinated α-tubulin, and vimentin in CTCs: identification of the interaction between CTCs and blood cells through cytoskeletal elements

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Broncy L. et al.
Oncotarget 2018 Apr 13; 9(28): 20058–20074.
Single-cell genetic analysis validates cytopathological identification of circulating cancer cells in patients with clear cell renal cell carcinoma

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Diaz M. et al.
Applied Cancer Research (2018) 38:8
Circulating tumor cells as marker of poor prognosis in metastatic lung cancer: a pilot study

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Ilie M. et al.
Clinical Chemistry and Laboratory Medicine 2018 Feb, Epub
Use of circulating tumor cells in prospective clinical trials for NSCLC patients – standardization of the pre-analytical conditions
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Braun A.C. et al.
Cancer Biology & Therapy 2018, Epub
EGFR expression in circulating tumor cells from high-grade Metastatic Sarcomas
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Kallergi G. et al
Therapeutic Advances in Medical Oncology 2018, 10: 1–11
Evaluation of PD-L1/PD-1 on circulating tumor cells in patients with advanced non-small cell lung cancer.
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Van Der Toom E. et al
The Prostate 2017 Dec 07; 1-8
Analogous detection of circulating tumor cells using the AccuCyte®—CyteFinder® system and ISET system in patients with locally advanced and metastatic prostate cancer.
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Leroy S. et al
BMJ Open 2017 Oct 05; Epub ahead of print
Circulating tumour cells as a potential screening tool for lung cancer (the AIR study): protocol of a prospective multicentre cohort study in France
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Ilie M. et al
Annals of Oncology, 2017 Oct 9 ; Epub ahead of print
Detection of PD-L1 in circulating tumor cells and white blood cells from patients with advanced non-small cell lung cancer.
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Ried K. et al
Asian Pacific Journal of Cancer Prevention 2017 Aug 27; 18(8):2275-2285.
Screening for Circulating Tumour Cells Allows Early Detection of Cancer and Monitoring of Treatment Effectiveness: An Observational Study.
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Ferretti Fanelli M. et al
Head & Neck 2017 1:10.
Evaluation of incidence, significance, and prognostic role of circulating tumor microemboli and transforming growth factor-b receptor I in head and neck cancer.
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Poruk K. E. et al
Pancreas 2017;46: 943:947.
Circulating Epithelial Cells in Intraductal Papillary Mucinous Neoplasms and Cystic Pancreatic Lesions
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Corassa M. et al
Applied Cancer Research (2017) 37:12
Circulating tumor cells as a new and additional approach to follow-up patients with serous low-grade ovarian adenocarcinoma ? a case report and review of the literature.
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Matikas A. et al
Translational Oncology 2017 June 26; 10: 693-698.
Detection of KRAS Exon 2 Mutations in Circulating Tumor Cells Isolated by the ISET System from Patients with RAS Wild Type Metastatic Colorectal Cancer
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Pailler E. et al
Translational Oncology 2017 June 26; 10: 693-698.
Circulating Tumor Cells with Aberrant ALK Copy Number Predict Progression-Free Survival during Crizotinib Treatment in ALK-Rearranged Non-Small Cell Lung Cancer Patients
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Ilie M. et al
Oncotarget 2017 Feb 15. doi:10.18632/oncotarget.15345 [Epub ahead of print]
Expression of MET in circulating tumor cells correlates with expression in tumor tissue from advanced-stage lung cancer patients.
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Laget S. et al
PLoS ONE 12(1): e0169427 doi: 10.1371/journal.pone.0169427
Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion.
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Souza e Silva V. et al
Onco Targets Ther. 2016, Dec. 9: 7503–7513 doi: https://doi.org/10.2147/OTT.S115268
Early detection of poor outcome in patients with metastatic colorectal cancer: tumor kinetics evaluated by circulating tumor cells.
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Kallergi G. et al
Cell Physiol Biochem 2016;40:411-419 doi: 10.1159/000452556
Evaluation of Isolation Methods for Circulating Tumor Cells (CTCs).
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Williamson S.C. et al
Nat Commun. 2016 Nov 9;7:13322. doi: 10.1038/ncomms13322.
Vasculogenic mimicry in small cell lung cancer.
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Poruk K.E. et al
Clin Cancer Res. 2016 Oct 27. doi: clincanres.1467.2016.
Circulating Tumor Cells Expressing Markers of Tumor Initiating Cells Predict Poor Survival and Cancer Recurrence in Patients with Pancreatic Ductal Adenocarcinoma.
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Pailler E. et al
BMC Cancer 2016 Jul 14; 16(1):477. doi: 10.1186/s12885-016-2461-4
Method for semi-automated microscopy of filtration-enriched circulating tumor cells.
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Massard C. et al
Oncotarget 2016 Jul 4, Epub ahead of print. doi: 10.18632/oncotarget.10396.
Phenotypic and genetic heterogeneity of tumor tissue and circulating tumor cells in patients with metastatic castrationresistant prostate cancer: a report from the PETRUS prospective study.
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Morrow C.J. et al
Annals of Oncology 27: 1155-1160, 2016 doi:10.1093/annonc/mdw122
Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study
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Poruk K.E. et al
Annals of Surgery 2016, Jan 7 doi: 10.1097/SLA.0000000000001600
Circulating tumor cells phenotype predicts recurrence and survival in pancreatic adenocarcinoma
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Salvianti F. et al
Front Mol Bioscience 2016 Jan, 2:76 doi: 10.3359/fmolb.2015.00076
Methylated Cell-free DNA and circulating tumor cells in melanoma
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Hofman V. et al
Cancer Cytopathol 2015, Nov 20 doi: 10.1002/cncy.21651
Detection and characterization of circulating tumor cells in lung cancer: Why and how?
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Buim M.M.E. et al
Cancer Biol Therapy 2015 Aug 10, doi: 10.1080/15384047.2015.1070991
Detection of KRAS mutation in circulating tumor cells from patients with metastatical colorectal cancer
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Pailler E. et al
Ann Oncol 2015 Apr 06 doi:10.1093/annonc/mdv165
High level of chromosomal instability in circulating tumor cells of ROS1-Rearranged non-small-cell lung cancer
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Ali Abdallah E. et al
Intl J Cancer 2015 Feb, doi: 10.1002/ijc.29495
Thymidylate synthase expression in circulating tumor cells: a new tool to predict 5-Fluorouacil resistance in metastatic colorectal cancer patients
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Paterlini-Bréchot P.
Cancer Microenviron 2014 Dec, 7(3):161-76
Circulating Tumor Cells: Who is the killer?
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Ilie et al
Plos One 2014 Oct 31, 9(10):e111597
“Sentinel” circulating tumor cells allow early diagnosis of lung cancer in patients with chronic obstructive pulmonary disease
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Faugeroux et al
Frontiers in Oncology 2014 Nov 5, 4:281
Clinical utility of circulating tumor cells in ALK-positive non-small-cell lung cancer
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LeBleu et al
Nature Cell Biology 2014 DOI: 10.1038/ncb3039
PGC-1alpha mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to
promote metastasis.
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Domingos Chinen L et al
Onco Targets and Therapy 2014:7 1606-1617
Isolation, detection and immunomorphological characterization of circulating tumor cells (CTCs) from patients with different types of sarcoma using isolation by size of tumor cells: a window on sarcoma-cell invasion.
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Morris KL et al
Cancer Chemother Pharmacol.2014 Jun 13
Circulating biomarkers in hepatocellular carcinoma.
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Khoja L et al
Ann Oncol. 2014 Jun 6. pii: mdu207
Circulating tumor cells as tumor biomarkers in melanoma: detection methods and clinical relevance.
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Hofman V et al
Curr Mol Med. 2014 May;14(4):440-56
Detection of circulating tumor cells from lung cancer patients in the era of targeted therapy : promises, drawbacks and pitfalls.
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J. Cummings et al
BMC Cancer, 2014 Mar 28;14:226
Optimisation of an immunohistochemistry method for the determination of androgen receptor expression levels in circulating tumour cells
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Mazzini C. et al
Cancers (Basel) 2014 Feb 7;6(1):323-32
Circulating Tumor Cells Detection and Counting in Uveal Melanomas by a Filtration-Based Method.
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Chinen L. et al
J Thorac Dis. 2013 Oct;5(5):593-9
Cytokeratin-based CTC counting unrelated to clinical follow-up.
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Ma, Y.C. et al
Technol Cancer Res Treat. 2013 Aug;12(4):295-309
Recent Advances and Prospects in the Isolation by Size of Epithelial Tumor Cells (ISET) Methodology.
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Marchesi V.
Nat Rev Clin Oncol. 2013 Jul;10(7):366
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Pailler E. et al
J Clin Oncol. 2013 Jun 20;31(18):2273-81
Detection of circulating tumor cells harboring a unique ALK rearrangement in ALK-positive non–small-cell lung cancer.
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Costa D.
J Clin Oncol. 2013 Jun 20;31(18):2236-9
Identification of somatic genomic alterations in circulating tumors cells: another step forward in non-small-cell lung cancer?
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Hofman V. et al
J Invest Dermatol. 2013 May;133(5):1378-81
Usefulness of Immunocytochemistry for the detection of the BRAFV600E mutation in Circulating Tumor Cells from Metastatic Melanoma Patients.
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Khoja L. et al
Melanoma Res. 2013 Feb;24(1):40-6.
Prevalence and heterogeneity of circulating tumour cells in metastatic cutaneous melanoma.
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Ilie M. et al
Ann Oncol. 2012 Nov;23(11):2907-13
ALK-gene rearrangement: a comparative analysis on circulating tumour cells and tumour tissue from patients with lung adenocarcinoma
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Hofman V. et al
Cytopathology 2012 Feb;23(1):30-8
Morphological analysis of circulating tumor cells in patients undergoing surgery for non-small cell lung carcinoma using the isolation by size of epithelial tumor cell (ISET) method.
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Hou J-M. et al
J Clin Oncol. 2012 Feb 10;30(5):525-32
Clinical significance and molecular characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in patients with small-cell lung cancer.
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Krebs M. et al.
J Thorac Oncol, 2012 Feb;7(2):306-15
Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches.
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Khoja, L. et al
Br J Cancer 2012 Jan 31;106(3):508-16
A pilot study to explore circulating tumour cells in pancreatic cancer as a novel biomarker.
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Lecharpentier A. et al
British J. Cancer, 2011 Oct 25;105(9):1338-41
Detection of circulating tumor cells with a hybrid (i.e. epithelial/mesenchymal) phenotype in patients with metastatic non-small cell lung cancer.
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Hofman V. et al
Int J Cancer, 2011 Oct 1;129(7):1651-60
Detection of circulating tumor cells as a prognostic factor in patients undergoing radical surgery for non-small cell lung carcinoma: Comparison of the efficacy of the CellSearch AssayTMand the isolation by size of epithelial tumor cell method®
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Farace F. et al
Br J Cancer 2011 Sep 6;105(6):847-53
A Direct Comparison of CellSearchTM and ISET® for Circulating Tumour-Cell Detection in Patients with Metastatic Carcinomas.
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Paterlini-Bréchot P.
Future Oncol. 2011 Jul;7(7):849-71
Organ-specific markers in circulating tumor cell screening: an early indicator of metastasis-capable malignancy.
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JM. et al
Am J Pathol, 2011 Mar;178(3):989-96
Circulating Tumor Cells as a Window on Metastasis Biology in Lung Cancer.
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Hofman V. et al
Clin Cancer Res 2011 Feb 15;17(4):827-35
Preoperative circulating tumor cell detection using the isolation by size of epithelial tumor cell method for patients with lung cancer is a new prognostic biomarker.
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Hofman V. et al
Am J Clin Pathol, 2011 Jan;135(1):146-56
Cytopathologic Detection of Circulating Tumor Cells Using the Isolation by Size of Epithelial Tumor Cell Method.
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De Giorgi V. et al
J Invest Dermatol. 2010 Oct;130(10):2440-7 2010
Application of a filtration and isolation-by-size technique for the detection of criculating tumor cells in cutaneous melanoma.
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De Giorgi V. et al
Arch Dermatol. 2010 Oct;146(10):1120-4
Circulating benign nevus cells detected by ISET technique: warning for melanoma molecular diagnosis.
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Descamps V. et al
Arch Dermatol 2010 Oct;146(10):1156-7
ISET device: a useful tool to answer some questions about the biologic behavior of melanocytic nevus cells.
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Pinzani P. et al
Melanoma Res. 2010 Aug;20(4):303-10
Tyrosinase mRNA levels in the blood of uveal melanoma patients: correlation with the number of circulating tumor cells and tumor progression.
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Paterlini-Bréchot P. et Benali N.
Cancer Lett. 2007 Aug 18;253(2):180-204
Circulating Tumor Cells (CTC) detection: Clinical impact and future directions
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Pinzani P. et al
Hum Pathol. 2006 Jun;37(6):711-8
Isolation by size of epithelial tumor cells in peripheral blood of patients with breast cancer: correlation with real time reverse transcriptase-polymerase chain reaction results and feasibility of molecular analysis by laser microdisection.
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Lelièvre L. et al
Int J Gynecol Cancer 2004 Mar-Apr;14(2):229-33
Effect of laparoscopy versus laparotomy on circulating tumor cells using isolation by size of epithelial tumor cells.
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Vona G. et al
Hepatology 2004 Mar;39(3):792-7.
Impact of cytomorphological and molecular characterization of circulating tumor cells in patients with Primary Liver Cancer.
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Vona G. et al
Am J Pathol 2000 Jan;156(1):57-63
ISET, Isolation by Size of Epithelial Tumor cells: a new method for isolation, immuno-morphological and molecular characterization of circulating tumor cells.
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